By Ralph W. Gerard M.D. (auth.), Joseph Wortis M.D. (eds.)
A approach to behavioral keep an eye on which makes use of nutritive sucking because the operant has been developed in our laboratory. utilizing this system we studied the position of arousal and studying within the improvement of environ psychological keep an eye on over earliest feeding habit. Few of the babies in our reviews have been in a position to coordinate their sucking habit to arbitrary operant-discrimination schedules, but if the person development of suck ing used to be considered, a few babies quickly tailored to the reinforcement time table. facts from numerous reinforcement schedules recommend that earliest mothering includes a mutual version within which the nurturing surroundings approximates after which entrains the infant's feeding habit by means of a perceptive manipulation of the infant's kingdom of arousal. Coordination among the baby and its atmosphere units the degree for associative studying, which develops following maturation of the infant's discriminative and reaction capacities. the method of behavioral acquisition starts off with unconditioned feeding responses, that are reworked into advanced realized habit in the course of the mediation of an competently reinforcing atmosphere. The babies studied confirmed person changes in susceptibility to environmental keep an eye on and in accordance with frustration. The relative significance of arousal and studying as determinants of boy or girl habit are mentioned and a hypothetical version for the earliest mother-infant courting is proposed.
Read or Download Recent Advances in Biological Psychiatry: The Proceedings of the Twenty-Second Annual Convention and Scientific Program of the Society of Biological Psychiatry, Detroit, Michigan, May 5–7, 1967 PDF
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2. Inhibition of highly purified pig-liver MAO by antidepressants at 31'C. The experimental procedure was the same as that described for Fig. I. The aliquot of enzyme used for eath assay corresponded to 11 flg of protein with a specific activity of 10. PT. II: PSYCHOPHARMACOLOGY 34 COIIPD. 75 NO. 77 x 10- 7 11 80 II 60 ____ 3 ____ 4 ____ ____ 6 5 ____ 7 8 pI Fig. 3. Inhibition of highly purified rabbit-liver MAO by antidepressants at 25°C. g protein) was preincubated for 10 min with inhibitor at the concentrations indicated along the abscissa and assayed for residual activity as described for Fig.
Using the tryptamine potentiation test [131. No. 2x 10- 7 M 1. 4 x 10- 7 M m 100 IV V VI SO 20 O~ ____ ~ 4 ____ ~ ____ 5 ~ 6 ____ ~ 7 ____ ~ 8 pI Fig. 2. Inhibition of highly purified pig-liver MAO by antidepressants at 31'C. The experimental procedure was the same as that described for Fig. I. The aliquot of enzyme used for eath assay corresponded to 11 flg of protein with a specific activity of 10. PT. II: PSYCHOPHARMACOLOGY 34 COIIPD. 75 NO. 77 x 10- 7 11 80 II 60 ____ 3 ____ 4 ____ ____ 6 5 ____ 7 8 pI Fig.
20:394, 1961. 20. : The effect of imipramine on the 5-hydroxytryptamine content and monoamine oxidase activity of the rat brain, J. Neurochem. 8:105, 1961. 21. : Human plasma monoamine oxidase. 1. Purification and identification, J. BioI. Chern. 240:2003, 1965. 22. : Interaction of D-cycloserlne with the action of some monoamine oxidase inhibitors. Biochem. Pharmacol. 14:1417, 1965. 23. : A comparison of the in vivo inhibition of brain and liver monoamine oxidase as produced by beta-phenylisopropylhydrazlne (PIH) and iproniazid, J.