By Shabir H. Lone, Khursheed Ahmad Bhat, Mohammad Akbar Khuroo
This publication studies the chemical and organic houses of Artemisia amygdalina Decne, a significantly endangered and endemic plant species within the the high-altitude Kashmir Himalayas, which has a excessive pharmacological power. It describes the bioactivity-guided isolation of its chemical substances, their characterization utilizing spectroscopic tools and the advance of an easy and trustworthy RP-HPLC technique for the simultaneous quantification of the remoted parts. The authors talk about the capability pharmacological actions of A. amygdalina, corresponding to antioxidant, cytotoxic, anti inflammatory, immuno-modulatory and antidiabetic results, and pave the way in which for destiny research.
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Extra resources for Chemical and Pharmacological Perspective of Artemisia amygdalina
2). 2 Structures of the isolated constituents from Artemisia amygdalina Decne H 28 4 Phytochemical Analysis and Chemobiological … been subjected to fractionation using flash chromatography system and afforded fraction I (4 g) and fraction II (10 g) with 5 and 15 % EtOAc-Hexane respectively. 5 g) and 6 (65 mg), while as that of fraction II yielded 1 (200 mg; also isolated from shoot). 2 and have been characterized using spectral data in the light of literature. 35 [M+] corresponding to molecular formula C28H46O, having melting point in the range 147–152 °C.
1997). Artemisias are popular plants, used for the treatment hepatitis, inflammation cancer, and infections by various microorganisms (Tan et al. 1998; Kim et al. 2002). An exhaustive literature survey has revealed that the genus Artemisia exhibits a vast array of biological activities mainly antimalarial, cytotoxic, antihepatotoxic, antibacterial, antifungal, antiinflammatory, and antioxidant. Terpenes, flavones, coumarins, and sterols are the main chemical classes present in various Artemisia species (Bora et al.
Concentrations of all the compounds have been calculated using linear regression equation of the calibration curves of the isolated compounds. The experiment has been triplicate for each day and also per day over a 3-day period. 3σ/S and LOQ = 10 σ/S where σ and S represent the standard deviation of response and the slope of the calibration curve, respectively. Based on the triplicate analysis carried out each day and also per day over a 3 day period, the intra as well as interday precision levels for the developed method was analyzed.