By Stephen Yazulla, Keith M. Studholme, Robert E. Marc, David Cameron
Chemical Anatomy of the Zebrafish Retina is a wonderful reference, offering very good pictures and perception into essentially the most more and more very important version structures in neurobiology this day. Papers contain a visually attractive molecular phenotype atlas and an exhaustive remedy of the neurochemical anatomy of the zebrafish retina as made up our minds via immunocytochemistry.
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Additional resources for Chemical Anatomy of the Zebrafish Retina
24C). This is very similar in appearance to that shown for GluR4-IR, NR2B-IR and Nall-IR (Figs. 11B, 12D and 23C). 4 co-localized with GluR4 in the dendrites of OFF bipolar cells. 2 subunit was concentrated in the area of cell bodies rather than in the synaptic layers (Fig. 24D). 2-IR appeared as "comma"-shaped structures in the OPLjINL border, the proximal INL and ganglion cell layer. Punctate label was present in the mid INL. This is similar to, but much weaker than observed in goldfish, in which the cell bodies of horizontal, amacrine cells and ganglion cells were labeled intensely at the same primary concentration (Yazulla & Studholme, 1999).
1985) Neuropeptide Y (NPY)-like immunoreactive amacrine cells in retinas of frog and goldfish. Cell & Tissue Research 241, 651-656. PATRECELLI, M. , LASHUEL, H. , GIANG, D. , KELLY, J. W. & CRAVATT, B. F. (1998) Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: Identification of the transmembrane domain as a site for oligomerization. Biochemistry 37, 15177-15187. PENG, Y. , BLACKSTONE, C. D. HUGANIR, R. L. & YAU, K. W. (1995) Distribution of glutamate receptor subtypes in the vertebrate retina.
The NR2B-IR structures had the same relationship with GluR2-IR as did GluR4-IR; both were surrounded. However, NR2B-IR appeared to be smaller and more concentrated in the center than GluR4-IR structures. Double labeling did not permit us to determine if NR2B-IR and GluR4-IR were on separate dendrites or on different parts of the same dendrite. The resolution to this issue will involve EM-ICC. GIuR4jPSD95 PSD95-IR was particularly faint, especially in horizontal sections. However, within the limits of resolution, it seemed clear that PSD95-IR and GluR4-IR co-localized (Fig.