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Download Biochemical Actions of Hormones. Volume 12 by Gerald, Litwack PDF

By Gerald, Litwack

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J. (1980). Ann. Ύ. Acad. Sei. 86, 205-219. Jones, B. , Stern, A. , Lewis, R. , and Shively, J. E. (1978). Arch. Biochem. Biophys. 204, 392-395. Jones, B. , Shively, J. , Kikpatrick, D. , and Udenfriend, S. (1982a). Proc. Natl. Acad. Set. A. 79, 1313-1315. Jones, B. , Shively, J. , Kilpatrick, D. , Stern, A. , Lewis, R. , and Udenfriend, S. (1982b). Proc. Natl. Acad. Sei. A. 79, 2096-2100. , and Numa, S. (1982). Nature (London) 298, 245-249. Kilpatrick, D. , Jones, B. , and Udenfriend, S. (1981a).

Stern, A. , Jones, B. , Shively, J. , and Udenfriend, S. (1980b). Froc. Natl. Acad. Set. A. 78, 1962-1966. , and Imura, H. (1981). Clin. Endocrinol. 15, 353-361. , and Imura, H. (1983). / . Clin. Endocrinol. Metab. 56, 1080-1083. , and Schwartz, J. P. (1983). Froc. Natl. Acad. Sei. A. 80, 3841-3844. Thomas, P. S. (1980). Froc. Natl. Acad. Sei. A. 77, 5201-5205. , and Kilpatrick, D. L. (1983). Arch. Biochem. Biophys. 221, 309-323. , and Ruddle, F. D. /. Biol. Chem. 258, 94449453. , and Wen, L. F.

APPROACHES TO THE STUDY O F PROCESSING OF OPIOID PEPTIDE PRECURSORS In order to determine the events involved in the processing of a protein precursor, it is necessary to have a system in which one can perform pulselabel and pulse-chase experiments. Most of the tissues that synthesize neuroendocrine precursors consist of mixed populations of cells in which the cells of interest comprise only a small proportion of the total population of cells. Tumor tissues and cell lines derived from precursor peptide-producing cells have been used as simplified model systems for the study of biosynthesis and the processing of neuroendocrine peptides because the cell population is relatively homogeneous.

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